:root {
    --main-light-purple: #a65387;
    --main-light-pink: #f7acb0;
    --main-dark-purple: #8d246a;
    --custom-success: #0cc485;
    --custom-info: #0d6efd;
    --nes-navy: #10344a;
    --nes-teal: #1c9fb3;
    --nes-teal-dark: #178294;
    --nes-text: #5b6b78;
}

/* Header & Footer */
#header .header-logo img {
    object-fit: contain;
    width: 100% !important;
}

.social-icons li:hover.social-icons-tiktok a {
    background: #151719 !important;
}

/* El override del breakpoint del header se genero con PHP en head.php,
   para poder controlarlo con la constante php HEADER_MOBILE_BREAKPOINT */

/* Home · Sección "Cáncer de páncreas"    */

.nes-pancreas {
    position: relative;
    padding: 90px 0 100px;
    background-image:
        linear-gradient(rgba(255, 255, 255, .3), rgba(255, 255, 255, .3)),
        url(../../assets/imagenes/contenido/tratamiento-innovador-cancer-pancreas-innovacancer-mexico2.webp);
    background-color: #ebf3f9;
    background-position: 100% 100%;
    background-size: cover;
    background-repeat: no-repeat;
    overflow: hidden;
}

@media (min-width: 1900px) {
    .nes-pancreas {
        background-position: 0 0;
    }
}

@media (max-width: 768px) {
    .nes-pancreas {
        background-image:
            linear-gradient(rgba(255, 255, 255, .7), rgba(255, 255, 255, .7)),
            url(../../assets/imagenes/contenido/tratamiento-innovador-cancer-pancreas-innovacancer-mexico2.webp);
    }
}

.nes-pancreas>.container {
    max-width: 1300px !important;
}

.nes-pancreas::before {
    content: "Ciencia\A Innovación\A Personas\A Vida";
    white-space: pre;
    position: absolute;
    top: 42px;
    left: 42px;
    text-transform: uppercase;
    font-family: 'Poppins', sans-serif;
    font-weight: 500;
    font-size: 15px;
    line-height: 2;
    letter-spacing: 2px;
    color: #93aabd;
    opacity: .75;
    pointer-events: none;
}

.nes-pancreas::after {
    content: "";
    position: absolute;
    top: 166px;
    left: 44px;
    width: 34px;
    height: 3px;
    background: var(--nes-teal);
    opacity: .85;
    pointer-events: none;
}

/* Encabezado central */
.nes-pancreas-head {
    max-width: 720px;
    margin-bottom: 55px;
}

.nes-overline {
    display: block;
    text-transform: uppercase;
    letter-spacing: 3px;
    font-weight: 600;
    font-size: 15px;
    color: var(--nes-teal);
    margin-bottom: 12px;
}

.nes-heading {
    font-family: 'Poppins', sans-serif;
    font-size: 56px;
    line-height: 1.05;
    color: var(--nes-navy);
    margin: 0 0 14px;
}

.nes-heading .nes-accent {
    color: var(--nes-teal);
}

.nes-subheading {
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    font-size: 25px;
    color: rgba(16, 52, 74, .68);
    margin: 0 0 18px;
}

.nes-lead {
    max-width: 640px;
    margin: 0 auto 22px;
    font-size: 17px;
    line-height: 1.7;
    color: var(--nes-text);
}

.nes-divider {
    display: block;
    width: 90px;
    height: 3px;
    margin: 0 auto;
    background: var(--nes-teal);
    border-radius: 2px;
}

/* Tarjetas */
.nes-cards {
    margin-bottom: 50px;
}

.nes-card {
    height: 100%;
    background: rgba(255, 255, 255, .97);
    border-radius: 16px;
    padding: 15px 20px;
    box-shadow: 0 18px 40px rgba(16, 52, 74, .08);
    transition: transform .25s ease, box-shadow .25s ease;
}

@media(max-width: 500px) {
    .nes-card>.row {
        flex-direction: column
    }

    .nes-card-icon img {
        max-width: 100px;
    }
}

.nes-card:hover {
    transform: translateY(-6px);
    box-shadow: 0 24px 50px rgba(16, 52, 74, .14);
}

.nes-card-head {
    display: flex;
    align-items: center;
    gap: 16px;
    margin-bottom: 16px;
}

.nes-card-icon {
    display: flex;
    flex: 0 0 auto;
    width: 100%;
    /* height: 64px; */
}

.nes-card-icon img {
    display: block;
    width: 100%;
    height: 100%;
    object-fit: contain;
}

.nes-card-title {
    margin: 0;
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    font-size: 20px;
    line-height: 1.25;
    text-transform: none;
    letter-spacing: 0;
    color: var(--nes-navy);
}

.nes-card-line {
    display: block;
    width: 46px;
    height: 3px;
    margin-bottom: 16px;
    background: var(--nes-teal);
    border-radius: 2px;
}

.nes-card-text {
    margin: 0;
    font-size: 15.5px;
    line-height: 1.65;
    color: var(--nes-text);
}

/* Botón */
.nes-btn-cta {
    display: inline-flex;
    align-items: center;
    gap: 12px;
    padding: 19px 44px;
    border-radius: 40px;
    background: var(--nes-teal);
    color: #fff !important;
    text-transform: uppercase;
    letter-spacing: 1.5px;
    font-weight: 600;
    font-size: 15px;
    text-decoration: none;
    box-shadow: 0 12px 26px rgba(28, 159, 179, .30);
    transition: background .25s ease, transform .25s ease, box-shadow .25s ease;
}

.nes-btn-cta:hover {
    background: var(--nes-teal-dark);
    transform: translateY(-2px);
    box-shadow: 0 14px 30px rgba(28, 159, 179, .4);
    color: #fff !important;
}

.nes-btn-cta i {
    transition: transform .25s ease;
}

.nes-btn-cta:hover i {
    transform: translateX(4px);
}

.nes-handwrite {
    position: absolute;
    right: 70px;
    bottom: 44px;
    margin: 0;
    color: #7d8c98;
    opacity: .7;
    font-size: 30px;
    line-height: 1.15;
    text-align: right;
    transform: rotate(-4deg);
    pointer-events: none;
}

@media (max-width: 991.98px) {
    .nes-pancreas {
        padding: 60px 0 70px;
    }

    .nes-heading {
        font-size: 40px;
    }

    .nes-subheading {
        font-size: 21px;
    }

    .nes-pancreas::before,
    .nes-pancreas::after,
    .nes-handwrite {
        display: none;
    }
}

.nes-values {
    background: #fff;
    padding: 46px 0;
}

.nes-value {
    text-align: center;
    padding: 12px 22px;
}

.nes-value-icon {
    display: inline-block;
    width: 72px;
    height: 72px;
    margin-bottom: 14px;
}

.nes-value-icon img {
    display: block;
    width: 100%;
    height: 100%;
    object-fit: contain;
}

.nes-value-title {
    margin: 0 0 6px;
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    font-size: 20px;
    text-transform: none;
    letter-spacing: 0;
    color: var(--nes-navy);
}

.nes-value-text {
    margin: 0;
    font-size: 14.5px;
    line-height: 1.5;
    color: var(--nes-text);
}

@media (min-width: 992px) {
    .nes-values .nes-value {
        position: relative;
    }

    .nes-values .nes-value:not(:last-child)::after {
        content: "";
        position: absolute;
        top: 50%;
        right: 0;
        transform: translateY(-50%);
        width: 1px;
        height: 90px;
        /* 👈 alto de la línea (súbelo/bájalo a gusto) */
        background: #dfe6ea;
    }
}

@media (max-width: 991.98px) {
    .nes-value {
        margin-bottom: 26px;
    }
}

/* Índice */
.nes-toc {
    background: #f6f8f9;
    border: 1px solid #e8edf0;
}

.nes-toc-title {
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    font-size: 22px;
    color: var(--nes-navy);
}

.nes-toc-toggle {
    color: var(--nes-teal);
    font-size: 20px;
    line-height: 1;
    cursor: pointer;
}

.nes-toc-toggle[aria-expanded="true"] .icon-closed,
.nes-toc-toggle[aria-expanded="false"] .icon-open {
    display: none;
}

/* Contenido */
.nes-toc-item {
    margin-bottom: 4px;
}

.nes-toc-item>a {
    display: flex;
    align-items: center;
    padding: 10px 14px;
    border-radius: 8px;
    font-family: 'Poppins', sans-serif;
    font-weight: 600;
    font-size: 16.5px;
    color: var(--nes-navy);
    text-decoration: none;
    transition: background .2s ease, color .2s ease;
}

.nes-toc-item>a::before {
    content: "";
    flex: 0 0 auto;
    width: 9px;
    height: 9px;
    margin-right: 12px;
    border-radius: 50%;
    background: var(--nes-teal);
}

.nes-toc-item>a:hover {
    background: rgba(28, 159, 179, .08);
    color: var(--nes-teal);
}

.nes-toc-sublist {
    margin: 2px 0 8px 34px;
}

.nes-toc-subitem>a {
    display: flex;
    align-items: center;
    padding: 7px 14px;
    border-radius: 8px;
    font-size: 15px;
    color: var(--nes-text);
    text-decoration: none;
    transition: background .2s ease, color .2s ease;
}

.nes-toc-subitem>a::before {
    content: "";
    flex: 0 0 auto;
    width: 6px;
    height: 6px;
    margin-right: 12px;
    border-radius: 50%;
    background: rgba(28, 159, 179, .55);
}

.nes-toc-subitem>a:hover {
    background: rgba(28, 159, 179, .08);
    color: var(--nes-teal);
}

.nes-content h2 {
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    text-transform: none;
    color: var(--nes-navy);
    font-size: 32px;
    line-height: 1.2;
    margin: 34px 0 14px;
}

.nes-content h3 {
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    text-transform: none;
    /* color: var(--nes-teal); */
    font-size: 23px;
    line-height: 1.3;
    margin: 28px 0 12px;
}

.nes-content h4:not(.card-title) {
    font-family: 'Poppins', sans-serif;
    font-weight: 700;
    text-transform: none;
    /* color: var(--nes-navy); */
    font-size: 19px;
    margin: 22px 0 10px;
}

.nes-content .nes-subhead {
    font-family: 'Poppins', sans-serif;
    font-weight: 600;
    text-transform: none;
    /* color: var(--nes-teal); */
    font-size: 16.5px;
    margin: 18px 0 8px;
}

.nes-content p {
    color: var(--nes-text);
    font-size: 16px;
    line-height: 1.75;
    margin-bottom: 14px;
}

.nes-content .nes-nodos>li,
.nes-content .nes-niveles>li {
    color: var(--nes-text);
    font-size: 16px;
    line-height: 1.7;
    margin-bottom: 10px;
}

.nes-content .nes-nodos>li strong,
.nes-content .nes-niveles>li strong {
    color: var(--nes-navy);
}

.nes-content figure img {
    box-shadow: 0 12px 30px rgba(16, 52, 74, .10);
}

.nes-content figcaption {
    max-width: 780px;
    margin: 10px auto 0;
    font-style: italic;
}

.accordion-nes.accordion-modern-status>.card .card-header a:not(.collapsed) {
    background-color: var(--nes-teal) !important;
    color: #fff !important;
}

.accordion-nes.accordion-modern-status>.card:hover .card-header a.collapsed {
    color: var(--nes-teal) !important;
}

/* FAQ */
.accordion-nes-faq .card-header a {
    color: var(--nes-navy) !important;
}

.accordion-nes-faq .card-header a:hover,
.accordion-nes-faq .card-header a:not(.collapsed) {
    color: var(--nes-teal) !important;
}

/*    Call to action */
.nes-cta {
    border-radius: 10px;
    padding: 34px 40px;
}

.nes-cta .call-to-action-content h3 {
    margin-top: 0;
}

.nes-cta .nes-cta-text {
    font-size: 17px;
    color: var(--nes-text);
}

.btn-nes {
    background-color: var(--nes-teal);
    border-color: var(--nes-teal);
    color: #fff;
    box-shadow: none;
    text-decoration: none;
    transition: background-color .25s ease, border-color .25s ease;
}

.btn-nes:hover,
.btn-nes:focus,
.btn-nes:active {
    background-color: var(--nes-teal-dark);
    border-color: var(--nes-teal-dark);
    color: #fff;
    box-shadow: none;
    text-decoration: none;
}